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Product Details
LETROZOL 2.5 mg by Balkan  Pharmaceuticals

LETROZOL 2.5 mg


Available Options:
Buy 10 tablets for $19.00
($1.90 each tablet)
Buy 50 tablets for $52.00
($1.04 each tablet)
Buy 100 tablets for $95.00
($0.95 each tablet)
[ If you need larger quantities email us for a quote ]

Product Specifications

Product: LETROZOL 2.5 mg
Product Code: P300-10
Manufacturer: Balkan Pharmaceuticals
Active Ingredient: letrozole
Strenght: 2.5 mg/tab

About letrozole

Letrozole is a type II (non-steroidal) third generation aromatase inhibitor. Clinically it is used to treat postmenopausal women with either estrogen receptor positive or estrogen receptor unknown breast cancer.

In women, tumors that contain estrogen receptors are classified as estrogen receptor-positive (ER+) tumors. For Letrozole to be prescribed, a given tumor must have been diagnosed as estrogen receptor positive or estrogen receptor unknown.

In the world of bodybuilding it is used to reduce or eliminate excess estrogen caused by the use of aromatizing steroids.

Background

Letrozole was originally sold under the brand name Femara, and produced by the pharmaceutical house Novartis. It was patented on July 25th, 1997.

Action

Letrozole is known as a type II aromatase inhibitor, meaning, in simplest terms that it attaches to the aromatase enzyme and prevents it from converting androgens to estrogen. In slightly more complex terms, estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme, and letrozole actually inhibits the production of estrogens in by competitive, (reversible) binding to the heme of the relevant cytochrome P450 unit.

Technical Data

Letrozole is currently the most powerful aromatase inhibitor available. In women with breast cancer, it has been shown to reduce estrogen levels by 98% or more. However, its use and benefits are not limited to eliminating estrogen in women.

In one male test subject Letrozole was able to reduce estrogen levels to undetectable levels, and in another clinical study done on both young and elderly men, intravenous administration of Letrozole lowered Estrogen by 46% in the young men tested, and 62% in the elderly subjects. Because estrogen is part of the negative feedback loop of the HPTA, Letrozole (and other anti-estrogens) are able to raise testosterone in male subjects. Letrozole was studied in men, and found to significantly increase LH levels to a 339 and 323% in the young and the elderly, respectively and Testosterone by 146 and 99%, respectively. Letrozole was also able to produce a peak LH response to Gonadatropin Releasing Hormone equal to a 152 and 52% increase from baseline in either young or older men, respectively. In a similar study 0.02 mg of Letrozole increased testosterone by 45% after 2 days. That same twenty micrograms of Letrozole was also enough, in one study done on men, to reduce estrogen levels by roughly a third.

Letrozole has a 2-4 day half-life, and it needs to be taken for up to 60 days to get a steady blood plasma level.

Letrozole was used in a rodent study to effectively destroy (benign) breast tissue tumors, which may potentially indicate its use in males attempting to remove gynecomastia (aka gyno).

As estrogen is also a factor in stopping linear bone growth, Letrozole is currently being examined for potential use in delay of growth seen in children.

About Balkan Pharmaceuticals

Balkan Pharmaceuticals is dedicated to provide high quality products for the global market and obtained lawful recognition of their operations in 2007 by the government of the Republic of Moldova.

Established under a mission of service to humanity, Balkan Pharmaceuticals is dedicated to providing a wide range of pharmaceuticals and is building a reputation of quality and integrity known around the world. They have assembled a staff of highly trained, dedicated individuals for the development, testing, and manufacture of life enhancing pharmaceuticals.

Balkan Pharmaceuticals is dedicated to meeting GMP standards set by the highest global authorities and has achieved full recognition of those authorities.

In addition, Balkan Pharmaceuticals is pursuing expansion, both in production facilities and in market area. Though currently authorized for distribution within Moldova only, they are actively working for their products to be approved in most of CIS nations.

Anti-Piracy

Each product manufactured by Balkan Pharmaceuticals has an Unique Product Identification Code (UPIC) printed on it that can be used for checking against Online UPIC Checking System. This way you can be sure that the product you use is legitimate.

[See all the available products for Balkan Pharmaceuticals]


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LETROZOL 2.5 mg by Balkan  Pharmaceuticals
  

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